Dr. Nan Zheng
Ohio University’s Chemistry and Biochemistry Colloquium Series presents Dr. Nan Zheng on “Development of New Chemistries of Photogenerated Distonic Amine Radical Cations: From Mechanistic Investigation to Synthetic Applications” on Monday, Oct. 9, at 4:10 p.m. in Clippinger Laboratories 194.
Zheng is Associate Professor Organic Chemistry and J. William Fulbright College of Arts and Sciences at the University of Arkansas.
Abstract: Amines are readily oxidized to amine radical cations by visible light photoredox catalysis. Taking advantage of this facile redox process, we have applied it to ring opening of cyclopropylanilines and cyclobutylanilines, which produces distonic amine radical cations. Although bearing two reactive sites with opposite polarity, the chemistries involving this type of reactive intermediates has been quite limited. In this talk, I will discuss our efforts to understand the reactivity of the amine radical cations and orthogonally intercept them using a nucleophile and a radical trap to form two C-C bonds simultaneously.
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