Ohio University’s Chemistry and Biochemistry Colloquium Series presents Dr. Xiang Zhang on “Walking in the Woods of Metabolites with Mass Spectrometry” on Monday, Nov. 28, at 4:10 p.m. in Clippinger Laboratories Room 194.
Dr. Xiang Zhang
Zhang is Director of the CREAM Center, Analytical Chemistry: Bioanalytical Chemistry and Bioinformatics at the University of Louisville
Abstract: Metabolomics has emerged as the latest of the ‘omics disciplines for deciphering the complex time-related concentration, activity and flux of metabolites in biological systems. Currently, multiple analytical platforms such as liquid chromatography–mass spectrometry (LC-MS), gas chromatography–mass spectrometry (GC-MS) and nuclear magnetic resonance spectroscopy (NMR) are used in metabolomics for global metabolic profiling, targeted metabolomics and stable isotope assisted metabolomics (SIAM), to study metabolic regulation alteration in metabolome. In this presentation, I will introduce our efforts in developing bioanalytical platforms (GCxGC-MS and LCxLC-MS), bioinformatics, as well as their applications in analysis of biological samples for both disease biomarker discovery and elucidation of biochemical mechanisms.
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