The Chemistry & Biochemistry Department presents Dr. Leonard R. MacGillivray on “Crystal Engineering the Covalent Bond: Applications of Self-Assembly and Photochemistry” on April 20, at 4 p.m. in Walter 235.
Dr. Leonard MacGillivray
MacGillivray is Professor of Chemistry at the University of Iowa.
Abstract: A method being developed in our laboratory that enables noncovalent bonds to be utilized, in a general way, to direct the formation of covalent bonds will be described. We show how small organic molecules and inorganic complexes act as templates by assembling olefins into prescribed geometries in the solid state to undergo photochemically induced [2+2] cycloadditions. We demonstrate how the template method enables unique molecules (e.g. ladderanes, cyclophanes) to be generated stereospecifically, in quantitative yield, and gram amounts. Relevance of the method to the fields of chemical synthesis, green chemistry, and self-assembly will be discussed. Related work in the fields of organic semiconductors and pharmaceutics also will be presented.
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