The Mathematical Biology Seminar presents “Clustering In the Cell Division Cycle of Yeast” on Thursday, Oct. 9, at 5 p.m. at 219 Morton Hall.
Title: Clustering In the Cell Division Cycle of Yeast
Speakers are Xue Gong, Gregory Moses, and Denise Scalfano from Department of Mathematics at Ohio University.
Abstract: It has long been noted that the cell division cycle of yeast and yeast autonomous oscillations are correlated with one another, but only recently has any serious attempt to explain the correlations taken place. It was proposed, and later experimentally observed, that these correlations were due to clustering in the cell division cycle, and a feedback mechanism was proposed as the underlying cause of this phenomenon.
Over the course of the last decade, several related models have been investigated in depth. During this survey talk, we introduce the feedback mechanism, and summarize results from a number of published and upcoming papers of our group. In particular, we consider the stability of solutions, and, having found a region of parameter space where clustered solutions are stable, we consider the question of robustness of solutions under biologically motivated noise. Finally, we consider two related models, each defined by modifying parameter restraints in the original model.
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